Generics Not Equal to Brand-Name Drugs for Overactive Bladder
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May 05, 2009
A comparison of brand-name oxybutynin with generic substitutes for overactive bladder shows that the bioequivalence in generic formulations can vary from 80% to 125% of the branded drug, investigators announced here at the 2009 annual meeting of the American Urological Association... ..[read article]
Hot Flashes Lessened With Steroidal Antiandrogen for Prostate Cancer
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April 28, 2009
For men with prostate cancer undergoing androgen ablation, hot flashes are less intense and quality of life is better with leuprorelin plus the steroidal androgen blocker chlormadinone than with leuprorelin plus the nonsteroidal antiandrogen bicalutamide, a Japanese team reports in the March issue of Urology.. ..[read article]
Omega-3 kill cancer cells
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April 27, 2009
omega-3 fatty acid found in fish oils, has been shown to reduce the size of tumours and enhance the positive effects of the chemotherapy drug cisplatin, while limiting its harmful side effects. ..[read article]
Advanced Prostate Cancer May Improve with Hormone Therapy
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April 18, 2009
Androgen suppression of locally advanced prostate cancer appears to be more successful when treatment is prolonged, according to Canadian and US researchersIn a March 23rd online paper issued by the Journal of Clinical Oncology, Dr. Luis Souhami of Montreal General Hospital and colleagues report on a secondary analysis of data on 189 patients who had taken part in a randomized trial of therapy for locally advanced prostate cancer ..[read article]
New Drug Targets Advanced Prostate Cancer
Scientists are developing a new drug to slow advanced prostate cancer that resists other androgen hormone treatment,In the advance online edition of Science, researchers report initial results from the first test if the drug, called MDV3100, in men with advanced prostate cancer ..
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April 13, 2009
New Drug Targets Advanced Prostate CancerScientists are developing a new drug to slow advanced prostate cancer that resists other androgen hormone treatment,In the advance online edition of Science, researchers report initial results from the first test if the drug, called MDV3100, in men with advanced prostate cancer ..
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New Polymorphisms Affect Colorectal Cancer Risk, Progression in Blacks
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April 06, 2009
The first study to investigate codon 72 variants of the p53 gene for the prognosis of colorectal cancer (CRC) in both white and black patients has identified a phenotype with independent prognostic value for black patients ..[read article]
Antitumor Effect of Paclitaxel in Ovarian Cancer
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April 05, 2009
an inhibitor of heparin-binding EGF-like factor (HB-EGF), is synergistic with paclitaxel against ovarian cancer, according to a report in the March 15th issue of the International Journal of Cancer ..[read article]
Esophageal Cancer Linked to Hot Tea Consumption
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April 05, 2009
Drinking hot tea was strongly associated with a higher risk for esophageal cancer according to the results of a northern Iranian population-based case-control study reported ..[read article]
Nitric oxide with vitamin B12 cytotoxic agent for cancer cells
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April 02, 2009
Nitric oxide cobine with a vitamin B12 (cyanocoblamine) calling Nitrosylcobalamin promising cytotoxic agent that targets cancer cells overexpressing B12 receptors, nitrosylcobalamin (NO-Cbl) -- has so far resulted in up to 77% cancer cell size reduction in 3 dogs that had ..[read article]
Gold Nanospheres Promising for Photoablation Cancer
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April 02, 2009
hollow gold nanospheres make them good candidates for biomedical imaging and treatment of cancer,The greatest challenge in developing an optimal light-absorbing material for use in photoablative cancer therapy "is to produce the hollow gold nanospheres with uniform shape, size, and wall ..[read article]
Colorectal Cancer Risk Increased With Endometrial Cancer
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March 30, 2009
Endometrial cancer is associated with an elevated risk of colorectal cancer, but not breast cancer, according to study results in the April issue of Obstetrics & Gynecology ..[read article]
New Mechanism May Explain Mixed Results With Integrin Inhibitors in Cancer Trials
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March 29, 2009
Data from a postmarketing analysis of reported adverse events showed no increased risk of cancer with ezetimibe (Zetia, Merck/Schering-Plough) or the combination of ezetimibe and simvastatin (Vytorin, Merck/Schering-Plough) [1]. Over a four-year period, the rates of cancer-associated adverse events and the ..[read article]
New Mechanism May Explain Mixed Results With Integrin Inhibitors in Cancer Trials
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March 29, 2009
Although several drugs that block angiogenesis have been successful in the treatment of cancer, there have also been some disappointments with this approach. In particular, 1 group of drugs developed to block angiogenesis — integrin inhibitors — has shown mixed results...[read article]
Additional Chemo Agent No Benefit in Advanced-Stage Ovarian Cancer
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March 20, 2009
The addition of a third cytotoxic agent to a standard treatment regimen of paclitaxel and carboplatin does nothing to improve overall or progression-free survival in women with advanced epithelial ovarian carcinoma, according to a multinational phase III trial published ahead of print on February 17 by the Journal of Clinical Oncology...[read article]
Selenium and Vitamin E Have Tissue Effects in Prostate Cancer Patients
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March 20, 2009
Gene expression profiles in prostatectomy specimens can provide insight into the effects of nutritional supplements taken by those patients preoperatively, according to the results of a new study...[read article]
Lymph Node Ratio Predicts Colorectal Cancer Survival
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FEB 25, 2009
Among patients with colorectal cancer, survival rates are associated with the lymph node ratio (LNR) -- i.e., the number of tumor-infiltrated nodes divided by the total number of resected nodes -- German researchers report in the December 2008 Annals of Surgery...[read article]
Saliva Proteins Could Help Detection Of Oral Cancer
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FEB 24, 2009
Clinicians could detect oral squamous cell carcinoma, a form of oral cancer, using a simple test that detects proteins in saliva, according to a report issue of Clinical Cancer Research, a journal of the American Association for Cancer Research. This work was led by David T. Wong ...[read article]
Embolization Remains Good Option for Unresectable Liver Cancer
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FEB 24, 2009
New research into transarterial chemoembolization, or the vascular delivery of chemotherapy to the liver using microspheres, shows promising results for patients with unresectable hepatocellular carcinoma ...[read article]
Extended Chemotherapy Increases Risk for Hepatic Injury
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FEB 23, 2009
The type of chemotherapy regimen has a greater impact on response than the duration of treatment after hepatic resection for colorectal liver metastases. In fact, extended preoperative chemotherapy increases the risk for hepatotoxicity in this population and does not improve pathologic response)...[read article]
Imatinib Suppresses Breast Cancer Bone Metastases by Inhibiting Osteoclasts
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FEB 22, 2009
Imatinib mesylate suppresses bone metastases from breast cancer by blocking signals from the macrophage colony-stimulating factor (M-CSF) receptor c-Fms and thereby inhibiting osteoclasts, according to a report in the January 1st International Journal of Cancer...[read article]
Blueberries May Shrink Tumors in Babies
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FEB 20, 2009
Substances found in blueberries may inhibit the growth of blood vessel tumors in infants and children, a new study suggests.Ohio State University researchers say they found that feeding a blueberry extract to mice with blood vessel tumors safely decreased the size of the tumors and improved surviva ...[read article]
DNA Repair Gene Variants Influence Risk for Pancreatic Cancer
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FEB 18, 2009
Polymorphisms of genes responsible for DNA repair can alter an individual's risk for pancreatic cancer, according to research by scientists at the M.D. Anderson Cancer Center in Houston, Texas. Focusing on variants of DNA repair genes, researchers identified 2 single nucleotide ..[read article]
Recognizing Lymphedema Is Vital in Assisting Oncology Patients
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FEB 15, 2009
Oncologists who are alert to the signs and symptoms of cancer and cancer-treatment-related lymphedema can have a large impact on its course, because the chronic condition can be minimized if recognized and treated early, according to a review article on ...[read article]
Validation Of Blood Brain Barrier Vector Technology Data Presented At EORTC-NCI-AACR Symposium
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FEB 14, 2009
AngioChem, Inc., a clinical-stage biotechnology company dedicated to creating and developing new drugs to treat brain diseases, has announced that its lead product, ANG1005, is safe and well tolerated in patients with brain cancer treated to date. ANG1005 consists of a proprietary peptide vector ....[read article]
Pancreatic Cancer Risk May Be Increased By Hepatitis C
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FEB 12, 2009
A new study shows that infection with hepatitis C virus (HCV) increases a person's risk for a highly fatal cancer of the biliary tree, the bile carrying pathway between the liver and pancreas. This finding is in the January issue of Hepatology, a journal published by John Wiley & Sons on ...[read article]
Cancer Groups Collaborate For Initiative To Boost Number Of Minority Oncologists
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FEB 10, 2009
Susan G. Komen for the Cure and the American Society of Clinical Oncology have partnered to create the Komen/ASCO Diversity in Oncology Initiative, which aims to reduce health care disparities by boosting the number of minority oncologists, the Cleveland Plain Dealer reports...[read article]
Side Effect Of Anticancer Therapy Highlighted During Breast Cancer Awareness Month
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FEB 10, 2009
As millions of Americans participate in educational initiatives as part of National Breast Cancer Awareness Month, they should keep in mind an important yet under-recognized consequence of breast cancer therapy: oral mucositis, one of the most common and debilitating side effects of cancer treatment...[read article]
