Hyaluronic Acid May Help Heal Chondral Injuries
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April 25, 2009
Intra-articular hyaluronic acid injection after microfracture treatment of experimental articular cartilage lesions appears to be helpful in rabbits.....[read article]
Zoledronic Acid Infusion Effective for Bone Loss Linked With Glucocorticoid Use
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April 25, 2009
A single 5-mg intravenous infusion of zoledronic acid was at least as effective and more acceptable to patients than 5 mg of oral risedronate daily to prevent and treat glucocorticoid-related bone loss, according to the results of a 1-year, noninferiority, double-blind, double-dummy, randomized controlled trial reported in the April 10 issue of The Lancet.....[read article]
Growth Factor Gene Therapy Delivered Locally to Periodontal Bone Lesions
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April 25, 2009
Experiments in rats show that human platelet-derived growth factor-B (PDGF-B) can be safely delivered by adenovirus in a collagen matrix to tooth-supporting alveolar bone defects, according to a report scheduled for publication in the May issue of Human Gene Therapy....[read article]
Bone Health Management Suboptimal in Prostate Cancer Patients
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April 18, 2009
Few men with prostate cancer undergoing androgen-deprivation therapy (ADT) are told about effects on bone density, and prevention efforts are not usual, according to a report in the March issue of BJU International....[read article]
Oral Bisphosphonate Use Linked to Jaw Osteonecrosis
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FEB 25, 2009
Oral treatment with the bisphosphonate alendronate (Fosamax, Merck) for as little as 1 year increases the risk for osteonecrosis of the jaw following certain dental procedures, according to a study conducted at the University of Southern California School of Dentistry in Los Angeles...[read article]
FDA Approves Tramadol Extended-Release Formulation for Chronic Pain
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FEB 24, 2009
Labopharm announced that the Food and Drug Administration (FDA) has approved an extended-release once-daily formulation of tramadol (Ryzolt) for the management of moderate to moderately severe chronic pain.
The new formulation of tramadol uses ...[read article]
Ultrasound Tracks Icatibant Effects in Osteoarthritis
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FEB 23, 2009
For the most part, contrast-enhanced ultrasound (CE-US) performs as well as contrast-enhanced magnetic resonance imaging (CE-MRI) in monitoring the action of the bradykinin receptor 2 antagonist icatibant in patients with painful knee osteoarthritis, German researchers report)...[read article]
Bisphosphonates Increase Rather Than Decrease Number of Osteoclasts
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FEB 21, 2009
Findings from a study of bone biopsies from women who took alendronate to prevent postmenopausal osteoporosis indicate that long-term treatment with the bisphosphonate actually increases rather than decreases the number of osteoclasts, as had been theorized...[read article]
eight-Bearing Exercise During Adolescence Benefits Bones Decades Later
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FEB 20, 2009
Women who participated in weight-bearing sports during their teens, the formative years for bone growth, have stronger bones after menopause than women who participated in lighter activities during their youth ...[read article]
Improving Safety When Using Bone And Soft Tissue Allograft
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FEB 18, 2009
Each year in the United States more than 1.3 million donated bone and bone-related allografts are successfully implanted in orthopaedic patients. Musculoskeletal allografts are frequently used in orthopaedic surgery to replace bones, tendons, or other soft tissues damaged by trauma, tumors or sports related injuries...[read article]
Bayer's Novel Anticoagulant Xarelto® Now Also Approved In The EU
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FEB 15, 2009
The Bayer Group has achieved a major success in its product development: The European Commission has granted marketing approval for Xarelto® (rivaroxaban), a novel anticoagulant taken as one tablet, once-daily, for the prevention of venous blood clots in adult patients undergoing elective (planned) hip or knee replacement surgery. Bayer HealthCare will start launching the product in the EU member states very soon...[read article]
Vitamin D Deficiency Common In Patients With IBD, Chronic Liver Disease
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FEB 12, 2009
New research presented at the 73rd Annual Scientific Meeting of the American College of Gastroenterology in Orlando found patients with inflammatory bowel disease or chronic liver disease were at increased risk of developing Vitamin D deficiencies....[read article]
Vitamin K, Osteoporosis, And Postmenopausal Women
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FEB 11, 2009
According to a new study published in the open-access journal PLoS Medicine, postmenopausal women with osteopenia did not prevent age-related bone mineral density (BMD) decline after taking a daily high dose supplement of vitamin K1. However, Angela Cheung (University of Toronto) and colleagues also found that...[read article]
